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Most vaccines -- and boosters -- are injected directly into muscle tissue, usually in the upper arm, to kickstart the body's immune system in the fight against disease. But for respiratory diseases like COVID-19, it can be important to have protection right where the virus enters: the respiratory tract. In a new study, researchers found that nasal vaccine boosters can trigger strong immune defenses in the respiratory tract, even without the help of immune-boosting ingredients known as adjuvants. The findings, researchers suggest, may offer critical insights into developing safer, more effective nasal vaccines in the future.

An international team of scientists has identified an unexpected region of heavy, neutron-deficient isotopes in the nuclear chart where nuclear fission is predominantly governed by an asymmetric mode.

A new study examined associations between diet, drinking water, and 'legacy' PFAS -- chemicals that were phased out of production in the US in the 2000s -- with blood samples from California residents. PFAS exposure was associated with consumption of seafood, eggs, and brown rice, but fewer other foods than suggested by earlier studies. PFAS levels were elevated among people who lived in areas where these chemicals were detectable in their drinking water supply, but lower than levels found in highly contaminated communities.

A surprising connection has been found, between two seemingly very different classes of superconductors. In a new material, atoms are distributed irregularly, but still manage to create long-range magnetic order.

A groundbreaking experiment--reveals 'symmetry' in physics doesn't always behave as scientists once believed.

A team of engineers has developed a system that could transform desalination practices, making the process more adaptable, resilient and cheaper. The new system is powered by sunlight and uses a creative approach to heat recovery for extended water production -- with and without sunshine.

The connection between a crumpled sheet of paper and quantum technology: A research team at the EPFL in Lausanne (Switzerland) and the University of Konstanz (Germany) uses topology in microwave photonics to make improved systems of coupled cavity arrays.

New research demonstrates shipborne navigation systems have potential to improve tsunami detection and warning.

Scientists have created a new nanoparticle that could make ultrasound-based cancer treatments more effective and safer, while also helping prevent tumors from coming back. To make the therapy even more powerful, the scientists also attached a potent chemotherapy drug to the peptide on the nanoparticle's surface. The ultrasound physically destroys the tumor, and the drug helps eliminate any leftover cancer cells that might cause the tumor to return.

Listen to the first notes of an old, beloved song. Can you name that tune? If you can, congratulations -- it's a triumph of your associative memory, in which one piece of information (the first few notes) triggers the memory of the entire pattern (the song), without you actually having to hear the rest of the song again. We use this handy neural mechanism to learn, remember, solve problems and generally navigate our reality.

Scientists inspired by the octopus's nervous system have developed a robot that can decide how to move or grip objects by sensing its environment.

For millions of people around the world with essential tremor, everyday activities from eating and drinking to dressing and doing basic tasks can become impossible. This common neurological movement disorder causes uncontrollable shaking, most often in the hands, but it can also occur in the arms, legs, head, voice, or torso. Essential tremor impacts an estimated 1 percent of the worldwide population and around 5 percent of people over 60. Investigators have now identified a specific subregion of the brain's thalamus that, when included during magnetic resonance-guided focused ultrasound (MRgFUS) treatment, can result in optimal and significant tremor improvements while reducing side effects.

Magnetic resonance imaging (MRI) scans of the heart could help to detect a life-threatening heart disease and enable clinicians to better predict which patients are most at risk, according to a new study.

Australian researchers have flagged some promising new approaches to treat severe burns that could save lives and dramatically improve patient recovery.

Researchers have developed a digital laboratory (dLab) system that fully automates the material synthesis and structural, physical property evaluation of thin-film samples. With dLab, the team can autonomously synthesize thin-film samples and measure their material properties. The team's dLab system demonstrates advanced automatic and autonomous material synthesis for data- and robot-driven materials science.

New device can give peace of mind and reduce anxiety for breastfeeding moms. It uses bioimpedance, which is currently used to measure body fat, and streams clinical-grade data to a smartphone or tablet in real time. Developed by physicians and engineers, device was tested by new moms. Technology could particularly benefit fragile babies in the NICU, who have precise nutritional needs.

An international team of researchers has discovered saarvienin A, a new type of glycopeptide antibiotic. Their findings introduce a compound with strong activity against highly resistant bacterial strains.

In many neurodegenerative diseases, proteins misfold and clump together in brain tissue. Scientists developed a new therapy made of peptides and a sugar that naturally occurs in plants. The therapeutic molecules self-assemble into nanofibers, which bond to the neuron-killing proteins. Now trapped, the toxic proteins can no longer enter neurons and instead harmlessly degrade.

When biting into a chili pepper, you expect a fiery sensation on your tongue. This spiciness is detected because of capsaicinoid compounds. But for some peppers, despite high levels of capsaicinoids, the heat is mysteriously dull. Now, researchers have identified three compounds that lessen peppers' pungency. These results challenge the reliability of the century-old Scoville scale, which traditionally bases its rating on two capsaicinoids.

Using a new fluorescent mouse model with advanced imaging techniques, researchers have successfully visualized how musculoskeletal components are integrated into the functional locomotor system during embryonic development.